Endocrine Abstracts

A 32 year-old man was referred with complaints of weight gain, sweating and a rash. Examination revealed a moon face, hypertension, centripetal obesity, a dorsal fat pad, and violaceous abdominal striae. A diagnosis of Cushing's syndrome was suspected.Urine free cortisol was elevated (3674 nmol/24hrs) with an unsuppressed ACTH level (39ng/l). Serum and urine cortisol failed to suppress with low and high dose dexamethasone. Corticotrophin Releasing Factor...

We audited the management of primary hyperparathyroidism (PHP) at our institution between 2000 and June 2004, to determine our adherence to the Consensus Development Conference on the Management of Asymptomatic PHP (2002) guidelines.Sixteen patients were referred with PHP during the period in question, 12 female. Average age at diagnosis was 59 years (range 36-81), average PTH level 155 ng/mL, and average corrected serum calcium 2.76 mmol/L (normal 2.1-2...

Studies in the general population have shown a prevalence of the metabolic syndrome of 17-25%. We have studied the prevalence of the metabolic syndrome in patients with diabetes mellitus (DM). A total of 150 consecutive patients with type 1 (21%) or type 2 DM (79%), mean age 59.1y (28-85), attending for annual review were studied to determine if they satisfy (ATP III) diagnostic criteria for the metabolic syndrome. Fasting plasma glucose, triglycerides, HDL cholesterol, blood ...